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etravirine will decrease the extent or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.Lonafarnib may possibly boost the AUC and peak concentration of CYP2C19 substrates. If coadministration unavoidable, check for adverse reactions and reduce the CYP2C19 substrate dose in accordance with its permitte

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